Efficient Palladium-Catalysed Enamide Synthesis from Enol Triflates and Enol Tosylates
Michael C. Willis*, Gareth N. Brace, Ian P. Holmes
*Department of Chemistry, University of Bath, Bath, BA2 7AY, UK, Email: m.c.willisbath.ac.uk
M. C. Willis, G. N. Brace, I. P. Holmes, Synthesis, 2005, 3229-3234.
DOI: 10.1055/s-2005-918480
Abstract
Catalysts generated from Pd2(dba)3 and biphenyl ligands efficiently promote the coupling of amides and carbamates with unactivated vinyl triflates and tosylates, to provide enamides in good to excellent yields.
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Key Words
enamides, carbamates, palladium, catalysis, enol triflates, enol tosylates
ID: J66-Y2005-2080