Organic Chemistry Portal



Soluble Lanthanide Salts (LnCl3•2 LiCl) for the Improved Addition of Organomagnesium Reagents to Carbonyl Compounds

Arkady Krasovskiy, Felix Kopp, Paul Knochel*

*Ludwig-Maximilians-Universität München, Department Chemie, Butenandtstrasse 5-13, Haus F, 81377 München, Germany, Email:

A. Krasovskiy, F. Kopp, P. Knochel, Angew. Chem. Int. Ed., 2006, 45, 497-500.

DOI: 10.1002/anie.200502485


LnCl3•2 LiCl (Ln = La, Ce, Nd) are superior promoter for the addition of various organometallic reagents to ketones. They also catalyze efficiently the addition of organomagnesium compounds to imines.

see article for more examples

Key Words

1,2-additions (to ketones, imines), enols, Grignard reaction, imines, lanthanides

ID: J06-Y2006-070