Expanding the Scope of Lewis Acid Catalysis in Water: Remarkable Ligand Acceleration of Aqueous Ytterbium Triflate Catalyzed Michael Addition Reactions
Rui Ding, Kambiz Katebzadeh, Lisa Roman, Karl-Erik Bergquist and Ulf M. Lindström*
*Department of Organic Chemistry, Lund University, P.O. Box 124, SE-221 00
Lund, Sweden, Email: ulf.lindstrom
organic.lu.se
R. Ding, K. Katebzadeh, L. Roman, K.-E. Bergquist, U. M. Lindström, J. Org. Chem., 2006, 71, 352-355.
DOI: 10.1021/jo051540n
Abstract
Addition of small dibasic ligands led to a significant rate acceleration of metal-catalyzed Michael addition reactions in water. Ytterbium triflate and TMEDA was the most effective combination.
see article for more examples
While ads financed 62% of the published abstracts in 2024, donations allowed us to publish additional 12%. 26% of the abstracts have been published voluntarly. If you kindly donate, we can publish more freely accessible information and help the chemical community even more:
If you don't like pawalls or a flood of more and more advertising, then you can send a clear signal here!
Key Words
Michael Addition, Active methylene compounds
ID: J48-Y2006-090
