Organic Chemistry Portal

Abstracts

Search:

New Functionalised Hydroxymethyl Ketones from the Mild and Chemoselective KMnO4 Oxidation of Chiral Terminal Olefins

Carlo Bonini *, Lucia Chiummiento, Maria Funicello, Paolo Lupattelli, Maddalena Pullez

*Dipartimento di Chimica, UniversitÓ degli Studi della Basilicata, Via N. Sauro 85, 85100 Potenza, Italy, Email: boniniunibas.it

C. Bonini, L. Chiummiento, M. Funicello, P. Lupattelli, M. Pullez, Eur. J. Org. Chem., 2006, 80-83.

DOI: 10.1002/ejoc.200500737


Abstract

Various terminal olefinic compounds are directly converted into the corresponding α-hydroxy ketones in good yields by potassium permanganate oxidation. The reaction is highly chemoselective in the presence of differently protected hydroxy groups.

see article for more examples



Key Words

Oxidation, Potassium Permanganate, Terminal Olefins, Hydroxymethyl Ketones (α-Hydroxylation) , Polyols


ID: J24-Y2006-180