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Molecular iodine: a highly efficient catalyst in the synthesis of quinolines via Friedlšnder annulation

Jie Wu*, Hong-Guang Xia and Ke Gao

*Department of Chemistry, Fudan University, 220 Handan Road, Shanghai, 200433, China, Email:

J. Wu, H.-G. Xia, K. Gao, Org. Biomol. Chem., 2006, 4, 126-129.

DOI: 10.1039/b514635f


A mild and efficient route for the synthesis of quinolines and polycyclic quinolines via Friedlšnder annulation, utilizing molecular iodine (1 mol%) as a new catalyst, is described.

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Key Words

Friedlaender Synthesis, Quinolines

ID: J52-Y2006-210