Enantioselective Nazarov Reactions through Catalytic Asymmetric Proton Transfer
Guangxin Liang and Dirk Trauner*
*Center for New Directions in Organic Synthesis, Department of Chemistry, University of California, Berkeley, California 94720-1460, Email: traunercchem.berkeley.edu
G. Liang, D. Trauner, J. Am. Chem. Soc., 2004, 126, 9544-9545.
DOI: 10.1021/ja0476664 (free Supporting Information)
A catalytic asymmetric Nazarov reaction is described that requires only 10 mol % of a chiral Lewis acid and proceeds with ee's between 72% and 97%.
see article for more examples