[3+2] Cross-Coupling Reactions of Aziridines with Isocyanates Catalyzed by Nickel(II) Iodide
Takeshi Munegumi, Isao Azumaya, Takako Kato, Hyuma Masu and Shinichi Saito*
*Department of Chemistry, Faculty of Science, Tokyo University of Science,
Kagurazaka, Shinjuku, Tokyo, Japan 162-8601, Email: ssaito
rs.kagu.tus.ac.jp
T. Munegumi, I. Azumaya, T. Kato, H. Masu, S. Saito, Org. Lett., 2006, 8, 379-382.
DOI: 10.1021/ol052417l
Abstract
A nickel-catalyzed cycloaddition of aziridines with isocyanates proceeded smoothly to give iminooxazolidine derivatives in good yields. A longer reaction time allowed the isomerization of the iminooxazolidine to the corresponding imidazolidinone derivatives.
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Key Words
Aziridines, Isocyanates, N-Heterocycles, O-Heterocycles, Oxazolidinones, Imidazolidinones
ID: J54-Y2006-350
