Iodoxybenzoic Acid (IBX): An Efficient and Novel Oxidizing Agent for the Aromatization of 1,4-Dihydropyridines
J. S. Yadav*, B. V. S. Reddy, A. K. Basak, G. Baishya, A. Venkat Narsaiah
*Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500007, India, Email: jsyadaviict.res.in
J. S. Yadav, B. V. S. Reddy, A. K. Basak, G. Baishya, A. V. Narsaiah, Synthesis, 2006, 451-454.
Hantzsch 1,4-dihydropyridines undergo smooth aromatization catalyzed by iodoxybenzoic acid (IBX) to afford the corresponding pyridine derivatives in high yields. All the reactions were carried out in DMSO solvent at 80-85 °C for a period of two to four hours to complete conversion of the substrates.
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