Brønsted Guanidine Acid-Base Ionic Liquids: Novel Reaction Media for the Palladium-Catalyzed Heck Reaction

Shenghai Li, Yingjie Lin, Haibo Xie, Suobo Zhang* and Jianing Xu

*State Key Laboratory of Polymer and Chemistry, Changchun Institute of Applied Chemistry, Changchun 130022, China, Email: sbzhangciac.jl.cn

S. Li, Y. Lin, H. Xie, S. Zhang, J. Xu, Org. Lett., 2006, 8, 391-394.

DOI: 10.1021/ol052543p

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Abstract

Brønsted acid-base ionic liquids (GILs) based on guanidine and acetic acid are efficient and reusable reaction media for palladium-catalyzed Heck reactions. These solvents play multiple roles: as strong bases and as ligands to stabilize Pd species.

see article for more examples

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Guanidine/Pd(OAc)₂-Catalyzed Room Temperature Suzuki Cross-Coupling Reaction in Aqueous Media under Aerobic Conditions

S. Li, Y. Lin, J. Cao, S. Zhang, J. Org. Chem., 2007, 72, 4067-4072.

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Key Words

Heck Reaction, Ionic Liquids

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ID: J54-Y2006-420