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Palladium-Catalyzed Hydroxycarbonylation of Aryl and Vinyl Triflates by in situ Generated Carbon Monoxide under Microwave Irradiation

Giordano Lesma, Alessandro Sacchetti, Alessandra Silvani*

*Dipartimento di Chimica Organica e Industriale e Centro Interdisciplinare Studi biomolecolari e applicazioni Industriali (CISI), UniversitÓ degli Studi di Milano, via G. Venezian 21, 20133 Milan, Italy, Email:

G. Lesma, A. Sacchetti, A. Silvani, Synthesis, 2006, 594-596.

DOI: 10.1055/s-2006-926288


An operationally simple hydroxycarbonylation of aryl and vinyl triflates to the corresponding carboxylic acids with a palladium-mediated microwave system was carried out in water.

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Key Words

carbonylations, carboxylic acids, microwaves, molybdenum hexacarbonyl, triflates

ID: J66-Y2006-480