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Novel, Efficient and Regiospecific Alkylation/Arylation/Heteroarylation of Unsymmetrical Azo Compounds

Olga Tšubrik, Rannar Sillard, Uno Mäeorg*

*Institute of Organic and Bioorganic Chemistry, University of Tartu, Jakobi 2, 51014 Tartu, Estonia, Email: uno.maeorgut.ee

O. Tšubrik, R. Sillard, U. Mäeorg, Synthesis, 2006, 843-846.

DOI: 10.1055/s-2006-926331


Abstract

Excellent regioselectivity is observed in the addition of diverse organometallic nucleophiles to unsymmetrical azo compounds. Primary/secondary/tertiary alkyl, aryl and heteroaryl substituents were introduced this way in high yields.

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Key Words

azo compounds, hydrazines, regioselectivity, neighboring group effects, protecting groups


ID: J66-Y2006-750