Mild Organocatalytic α-Methylenation of Aldehydes
Anniina Erkkilä and Petri M. Pihko*
*Laboratory of Organic Chemistry, Helsinki University of Technology, P.O.B.
6100, FI-02015 TKK, Finland, Email: petri.pihko
tkk.fi
A. Erkkilä, P. M. Pihko, J. Org. Chem., 2006, 71, 2538-2541.
DOI: 10.1021/jo052529q
Abstract
Two optimal catalytic systems for the convenient and fast α-methylenation of
aldehydes with aqueous formaldehyde are described that allow short reaction
times and afford the methylenated products in good to excellent yields and
chemoselectivity.
see article for more examples
Key Words
Enones, Methylenation, Organocatalysis
ID: J42-Y2006-860
