Improved Procedure for Palladium-Catalyzed Hiyama Cross-Coupling Reaction of Aryl Halides with Aryltrimethoxysilanes under Solvent-Free Conditions
Jin-Heng Li*, Chen-Liang Deng, Ye-Xiang Xie
*Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China, Email: jhlihunnu.edu.cn
J.-H. Li, C.-L. Deng, Y.-X. Xie, Synthesis, 2006, 969-974.
An efficient, solvent-free, palladium-catalyzed Hiyama cross-coupling reaction is reported. In the presence of PdCl2(MeCN)2, P(o-tol)3 and TBAF, a various aryl halides were coupled with arylsiloxanes to afford biaryls in moderate to excellent yields.
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