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A Convenient Protocol for the Alkylidenation of Lactams

Mark C. Elliott*, Stuart V. Wordingham

*School of Chemistry, Cardiff University, Park Place, Cardiff CF10 3AT, UK, Email:

M. C. Elliot, S. V. Wordingham, Synthesis, 2006, 1162-1170.

DOI: 10.1055/s-2006-926390


A convenient two-step preparation of alkylidenepyrrolidines is reported.

see article for more reactions

see article for more examples

Key Words

lactams, pyrrolidines, enamines, imides, enolates, aldol reactions, 1,3-diketones, β-keto esters

ID: J66-Y2006-1060