Oxidative Iodination of Deactivated Arenes in Concentrated Sulfuric Acid with I₂/NaIO₄ and KI/NaIO₄ Iodinating Systems

Lukasz Kraszkiewicz, Maciej Sosnowski, Lech Skulski*

*Chair and Laboratory of Organic Chemistry, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha Street, 02-097 Warsaw, Poland, Email: lechskulskiyahoo.com

L. Kraszkiewicz, M. Sosnowski, L. Skulski, Synthesis, 2006, 1195-1199.

DOI: 10.1055/s-2006-926374

---

Abstract

Deactivated arenes were mono- or diiodinated with strong electrophilic I⁺ reagents, which were prepared from NaIO₄ and either I₂ or KI in concentrated sulfuric acid, using either a ‘direct' or an ‘inverse' method of aromatic iodination to give mono- or diiodinated pure products in good yields.

see article for more examples

---

---

Key Words

iodoarenes, deactivated arenes, iodine, potassium iodide, sodium periodate, direct oxidative iodination

---

ID: J66-Y2006-1090