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Pd(0)-Catalyzed PMHS Reductions of Aromatic Acid Chlorides to Aldehydes

Kyoungsoo Lee and Robert E. Maleczka, Jr.*

*Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, Email:

K. Lee, R. E. Maleczka, Jr., Org. Lett., 2006, 8, 1887-1888.

DOI: 10.1021/ol060463v (free Supporting Information)


Polymethylhydrosiloxane (PMHS) under Pd(0) catalysis can efficiently reduce aryl acid chlorides to their corresponding aldehydes in the presence of fluoride without requiring an additional reductant.

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Key Words

Reduction of Acid Chlorides, PMHS

ID: J54-Y2006-1150