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Efficient Microwave-Assisted Solvent-Free Synthesis of N-Substituted Aldimines

Ludovic Paquin, Jack Hamelin, Françoise Texier-Boullet*

*Synthèse et Electrosynthèse organique 3, UMR 6510, CNRS et Université de Rennes 1, Campus de Beaulieu, 35042 Rennes, France, Email:

L. Paquin, J. Hamelin, F. Texier-Boullet, Synthesis, 2006, 1652-1656.

DOI: 10.1055/s-2006-926429


Neat non-volatile amines react efficiently with various aromatic aldehydes in the absence of any catalyst or solvent, to give imines after a reaction time of eight minutes under microwave irradiation. 1,3-dimethylurea dispersed on montmorillonite K10 is used as an methylamine precursor.

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Key Words

imines, microwave Synthesis, solvent-free reactions, ureas

ID: J66-Y2006-1380