Enantioselective One-Pot Three-Component Synthesis of Propargylamines
Alakesh Bisai and Vinod K. Singh*
*Department of Chemistry, Indian Institute of Technology, Kanpur, India 208 016, Email: vinodksiitk.ac.in
A. Bisai, V. K. Singh, Org. Lett., 2006, 8, 2405-2408.
DOI: 10.1021/ol060793f (free Supporting Information)
A copper(I) complex of i-Pr-pybox-diPh efficiently catalyzes the enantioselective one-pot three-component synthesis of propargylamines from aromatic aldehydes, anilines, and alkynes. A transition-state model has been proposed.
see article for more examples