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Synthesis of Benzoic Acids by Aerobic Photooxidation with Hydrobromic Acid

Shin-ichi Hirashima, Akichika Itoh*

*Gifu Pharmaceutical University, Mitahora-higashi, Gifu 502-8585, Japan, Email:

S.-I. Hirashima, A. Itoh, Synthesis, 2006, 1757-1759.

DOI: 10.1055/s-2006-942356


A methyl group at an aromatic nucleus is oxidized directly to the corresponding carboxylic acid in the presence of molecular oxygen and catalytic hydrobromic acid under photoirradiation.

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proposed reaction pathway

Key Words

aerobic, benzoic acids, hydrobromic acid, methyl group, photooxidation, Green Chemistry

ID: J66-Y2006-1510