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Grignard Reactions in Imidazolium Ionic Liquids

Scott T. Handy*

*Department of Chemistry, Middle Tennessee State University, Murfreesboro, Tennessee 37132, Email:

S. T. Handy, J. Org. Chem., 2006, 71, 4659-4662.

DOI: 10.1021/jo060536o


A new, base-stable, imidazolium room-temperature ionic liquid (RTIL) has been prepared and applied to the addition of Grignard reagents to carbonyl compounds to afford alcohol products in good to excellent yield at ambient temperature. The RTIL can be easily recycled and reused.

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Key Words

Grignard Reaction, Ionic Liquids

ID: J42-Y2006-1620