Ene Reaction of Arynes with Alkynes
Thiruvellore Thatai Jayanth, Masilamani Jeganmohan, Mu-Jeng Cheng, San-Yan Chu and Chien-Hong Cheng*
*Department of Chemistry, Tsing Hua University, Hsinchu 30013, Taiwan, Email: chchengmx.nthu.edu.tw
T. T. Jayanth, M. Jeganmohan, M.-J. Cheng, S.-Y. Chu, C.-H. Cheng, J. Am. Chem. Soc., 2006, 128, 2232-2233.
DOI: 10.1021/ja058418q (free Supporting Information)
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Arynes, generated in situ from ortho-silylaryl triflates, undergo ene reaction with alkynes possessing propargylic hydrogen in the presence of KF/18-crown-6 in THF at room temperature to give substituted phenylallenes in good to moderate yields.
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