Organic Chemistry Portal

Abstracts

Search:

Silver-Catalyzed Hydroamination of Siloxy Alkynes

Jianwei Sun, Sergey A. Kozmin*

*Department of Chemistry, University of Chicago, 5735 South Ellis Avenue, Chicago, IL 60637, USA, Email: skozminuchicago.edu

J. Sun, S. A. Kozmin, Angew. Chem. Int. Ed., 2006, 45, 4991-4993.

DOI: 10.1002/anie.200601276


Abstract

A silver-based catalyst promotes a syn-selective hydroamination of electron-rich alkynes with either secondary amides or carbamates. This method is efficient for the synthesis of various synthetically useful silyl ketene aminals. The mechanism is discussed.

see article for more reactions and examples



Key Words

ketene aminals, alkynes, homogeneous catalysis, hydroamination, silver


ID: J06-Y2006-2020