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Silver-Catalyzed Hydroamination of Siloxy Alkynes

Jianwei Sun, Sergey A. Kozmin*

*Department of Chemistry, University of Chicago, 5735 South Ellis Avenue, Chicago, IL 60637, USA, Email:

J. Sun, S. A. Kozmin, Angew. Chem. Int. Ed., 2006, 45, 4991-4993.

DOI: 10.1002/anie.200601276


A silver-based catalyst promotes a syn-selective hydroamination of electron-rich alkynes with either secondary amides or carbamates. This method is efficient for the synthesis of various synthetically useful silyl ketene aminals. The mechanism is discussed.

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Key Words

ketene aminals, alkynes, homogeneous catalysis, hydroamination, silver

ID: J06-Y2006-2020