HClO4-SiO2 as a new, highly efficient, inexpensive and reusable catalyst for N-tert-butoxycarbonylation of amines
Asit K. Chakraborti and Sunay V. Chankeshwara
*Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. A. S. Nagar 160 062, Punjab, India, Email: akchakrabortiniper.ac.in
A. K. Chakraborti, S. V. Chankeshwara, Org. Biomol. Chem., 2006, 4, 2769-2771.
DOI: 10.1039/b605074c (free Supporting Information)
Perchloric acid adsorbed on silica-gel (HClO4-SiO2) was found to be a new, highly efficient, inexpensive and reusable catalyst for chemoselective N-tert-butoxycarbonylation of amines at room temperature and under solvent-free conditions.
see article for more examples
S. V. Chankeshwara, A. K. Chakraborti, Org. Lett., 2006, 8, 3259-3262.
S. Rudrawar, R. C. Besra, A. K. Chakraborti, Synthesis, 2006, 2767-2771.