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Rhodium(I)-Catalyzed Carboxylation of Aryl- and Alkenylboronic Esters with CO2

Kazutoshi Ukai, Masao Aoki, Jun Takaya and Nobuharu Iwasawa*

*Department of Chemistry, Tokyo Institute of Technology, O-Okayama, Meguro-ku, Tokyo 152-8551, Japan, Email:

K. Ukai, M. Aoki, J. Takaya, N. Iwasawa, J. Am. Chem. Soc., 2006, 128, 8706-8707.

DOI: 10.1021/ja061232m (free Supporting Information)


Treatment of 2,2-dimethylpropan-1,3-diol esters of aryl- and alkenylboronic acids with a catalytic amount of [Rh(OH)(cod)]2 in the presence of 1,3-bis(diphenylphosphino)propane and CsF in dioxane at 60C under carbon dioxide atmosphere gave carboxylic acids in good yields.

see article for more examples

Copper(I)-Catalyzed Carboxylation of Aryl- and Alkenylboronic Esters

J. Takaya, K. Ukai, N. Iwasawa, Org. Lett., 2008, 10, 2697-2700.

Key Words

Boronates, Carboxylic Acids, Benzoic Acid Derivatives

ID: J48-Y2006-2180