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A Convenient Synthesis of 2,2-Diarylcyclobutanones by Cerium(IV) Ammonium Nitrate (CAN) Mediated Oxidation of Methylenecyclopropanes (MCPs)

Vijay Nair*, T. D. Suja, Kishor Mohanan

*Organic Chemistry Section, Regional Research Laboratory (CSIR), 695019 Trivandrum, India, Email:

V. Nair, T. D. Suja, K. Mohanan, Synthesis, 2006, 2531-2534.

DOI: 10.1055/s-2006-942445


Oxidative ring expansion of methylenecyclopropanes with CAN under oxygen atmosphere was investigated. A facile conversion affording 2,2-diarylcyclobutanones occurred in good yields.

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proposed mechanism

Key Words

CAN, methylenecyclopropane, cyclobutanones, oxygen, oxidative ring expansion, ketones

ID: J66-Y2006-2330