Radical-Mediated Alkenylation, Alkynylation, Methanimination, and Cyanation of B-Alkylcatecholboranes
Arnaud-Pierre Schaffner, Vincent Darmency, Philippe Renaud*
*Universität Bern, Departement für Chemie und Biochemie, Freiestrasse 3,
3000 Bern 9, Switzerland, Email: philippe.renaud
ioc.unibe.ch
A.-P. Schaffner, V. Darmency, P. Renaud, Angew. Chem. Int. Ed., 2006, 45, 5847-5849.
DOI: 10.1002/anie.200601206
see article for more reactions
Abstract
Hydroboration with catecholborane, followed by treatment with easily available reagents such as alkenyl sulfones or alkynyl phenyl sulfones in the presence of a radical initiator, represents an effective and simple one-pot procedure for direct vinylation, formylation, and cyanation.
see article for more examples
Key Words
CC coupling, hydroboration, olefination, radical reactions, vinylsulfones, oximes, alkynes, nitriles, catecholborane
ID: J06-Y2006-2630
