Cationic Rhodium(I)/Modified-BINAP Catalyzed [2+2+2] Cycloaddition of Alkynes with Nitriles

Ken Tanaka *, Nanami Suzuki, Goushi Nishida

*Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan, Email: tanaka-kcc.tuat.ac.jp

K. Tanaka, N. Suzuki, G. Nishida, Eur. J. Org. Chem., 2006, 3917-3922.

DOI: 10.1002/ejoc.200600347

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Abstract

Cationic rhodium(I)/modified-BINAP complexes catalyze a chemo- and regioselective [2+2+2] cycloaddition of a wide variety of alkynes and nitriles leading to highly functionalized pyridines under mild reaction conditions.

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A New Route to Substituted Phenols by Cationic Rhodium(I)/BINAP Complex-Catalyzed Decarboxylative [2 + 2 + 2] Cycloaddition

H. Hara, M. Hirano, K. Tanaka, Org. Lett., 2009, 11, 1337-1340.

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Key Words

Pyridines

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ID: J24-Y2006-2880