Pd-mBDPP-Catalyzed Regioselective Internal Arylation of Electron-Rich Olefins by Aryl Halides
Shifang Liu, Neil Berry, Nick Thomson, Alan Pettman, Zeynab Hyder, Jun Mo and Jianliang Xiao*
*Department of Chemistry, Liverpool Centre for Materials and Catalysis,
University of Liverpool, Liverpool L69 7ZD, U.K., Email: j.xiao
liv.ac.uk
S. Liu, N. Berry, N. Thomson, A. Pettman, Z. Hyder, J. Mo, J. Xiao, J. Org. Chem., 2006, 71, 7467-7470.
DOI: 10.1021/jo0609632
Abstract
meso-2,4-Bis(diphenylphosphino)pentane (mBDPP) is an effective regiocontrolling ligand for palladium-catalyzed internal arylation of electron-rich olefins in DMSO with no need for any halide scavengers.
see article for more examples
The Heck Reaction of Electron-Rich Olefins with Regiocontrol by Hydrogen-Bond Donors
J. Mo, J. Xiao, Angew. Chem. Int. Ed., 2006, 45, 4152-4157.
M. McConville, O. Saidi, J. Blacker, J. Xiao, J. Org. Chem., 2009, 74, 2692-2698.
Key Words
Heck reaction, homogeneous catalysis, regioselectivity, aryl ketones
ID: J42-Y2006-2930
