Organic Chemistry Portal



N-Heterocyclic Carbene Catalyzed Nucleophilic Substitution Reaction for Construction of Benzopyrones and Benzofuranones

Jinmei He, Jiyue Zheng, Jian Liu, Xuegong She* and Xinfu Pan

*Department of Chemistry, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000, P. R. China, Email:

J. He, J. Zheng, J. Liu, X. She, X. Pan, Org. Lett., 2006, 8, 4637-4640.

DOI: 10.1021/ol061924f (free Supporting Information)


An N-Heterocyclic carbene efficiently catalyzed an intramolecular nucleophilic substitution reaction to yield benzopyrones and benzofuranones depending on the substitution pattern.

see article for more examples

Key Words

Organocatalysis, Chromanones, Benzofuran-3(2H)-ones

ID: J54-Y2006-3040