Intermolecular Rhodium-Catalyzed Carbometalation/Heck-Type Reaction in Water
Takuya Kurahashi, Hiroshi Shinokubo* and Atsuhiro Osuka
*Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan, Email: hshinokuchem.kyoto-u.ac.jp
T. Kurahashi, H. Shinokubo, A. Osuka, Angew. Chem. Int. Ed., 2006, 45, 6336-6338.
DOI: 10.1002/anie.200602585 (free Supporting Information)
The rhodium-catalyzed reaction of aryl boronic acids with internal alkynes and acrylates in water gives the domino coupling products. The reaction demonstrates that water offers the possibility to discover novel transformations.
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