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A Highly Regioselective Salt-Free Iron-Catalyzed Allylic Alkylation

Bernd Plietker

*Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany, Email:

B. Plietker, Angew. Chem. Int. Ed., 2006, 45, 1469-1473.

DOI: 10.1002/anie.200503274


A salt-free, regioselective Fe-catalyzed allylic alkylation of allyl carbonates with active methylene compounds gave coupled products in good to excellent yields. Addition of triphenylphosphane led to a significant increase of the reactivity of the stable Fe(-II) complex.

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Regioselective Iron-Catalyzed Allylic Amination

B. Plietker, Angew. Chem. Int. Ed., 2006, 45, 6053-6056.

Key Words

active methylene compounds, iron, nucleophiles, regioselectivity

ID: J06-Y2006-3180