Silicon-Catalyzed Conversion of Nitro Compounds into Ketones and Poly(1,3-diketones)
Jih Ru Hwu*, Thainashmuthu Josephrajan, Shwu-Chen Tsay
*Department of Chemistry, National Tsing Hua University, Hsinchu 300, Taiwan, Email: jrhwumx.nthu.edu.tw
J. R. Hwu, T. Josephrajan, S.-C. Tsay, Synthesis, 2006, 3305-3308.
The reaction of various secondary nitro compounds with potassium hydride in 1,4-dioxane and subsequently with chlorotrimethylsilane gave the corresponding ketones in good yields. The use of a catalytic amount of chlorotrimethylsilane was the key to the success of this transformation.
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nitro compounds, ketones, poly(1,3-diketones), Nef reaction, silicon