Highly Efficient Oxidative Amidation of Aldehydes with Amine Hydrochloride Salts
Woo-Jin Yoo and Chao-Jun Li*
*Department of Chemistry, McGill University, Montreal, Quebec, Canada H3A
2K6, Email: cj.li
mcgill.ca
W.-J. Yoo, C.-J. Li, J. Am. Chem. Soc., 2006, 128, 13064-13065.
DOI: 10.1021/ja064315b
Abstract
A mild and efficient oxidative amidation of aldehydes uses amine HCl salts and tert-butyl hydroperoxide as an oxidant in the presence of a copper catalyst.
see article for more examples
proposed mechanism
Key Words
oxidative amidation, tert-butyl hydroperoxide
ID: J48-Y2006-3360
