Highly Efficient Oxidative Amidation of Aldehydes with Amine Hydrochloride Salts
Woo-Jin Yoo and Chao-Jun Li*
*Department of Chemistry, McGill University, Montreal, Quebec, Canada H3A 2K6, Email: cj.limcgill.ca
W.-J. Yoo, C.-J. Li, J. Am. Chem. Soc., 2006, 128, 13064-13065.
A mild and efficient oxidative amidation of aldehydes uses amine HCl salts and tert-butyl hydroperoxide as an oxidant in the presence of a copper catalyst.
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oxidative amidation, tert-butyl hydroperoxide