A New Method for the Synthesis of Functionalized 5-Hydroxy-1,5-dihydro-2H-pyrrol-2-one: Reaction of an Enamine, Derived from Addition of a Secondary Amine to Dibenzoylacetylene, with an Arylsulfonyl Isocyanate

Abdolali Alizadeh*, Farnaz Movahedi, Hassan Masrouri, Long-Guan Zhu

*Department of Chemistry, Tarbiat Modarres University, P. O. Box 14115-175, Tehran, Iran, Email: aalizadehmodares.ac.ir

A. Alizadeh, F. Movahedi, H. Masrouri, L.-G. Zhu, Synthesis, 2006, 3431-3436.

DOI: 10.1055/s-2006-950234

Abstract

An effective route to novel 5-hydroxy-1,5-dihydro-2H-pyrrol-2-one is described which involves the reaction of an enamine, derived from addition of a secondary amine to dibenzoylacetylene, with an arylsulfonyl isocyanate.

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Key Words

dibenzoylacetylene, secondary amines, isocyanates, 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones, N-Heterocycles

ID: J66-Y2006-3460

A New Method for the Synthesis of Functionalized 5-Hydroxy-1,5-dihydro-2H-pyrrol-2-one: Reaction of an Enamine, Derived from Addition of a Secondary­ Amine to Dibenzoylacetylene, with an Arylsulfonyl Isocyanate

Abdolali Alizadeh*, Farnaz Movahedi, Hassan Masrouri, Long-Guan Zhu

A New Method for the Synthesis of Functionalized 5-Hydroxy-1,5-dihydro-2H-pyrrol-2-one: Reaction of an Enamine, Derived from Addition of a Secondary Amine to Dibenzoylacetylene, with an Arylsulfonyl Isocyanate