1,1,1-Tris(hydroxymethyl)ethane as a New, Efficient, and Versatile Tripod Ligand for Copper-Catalyzed Cross-Coupling Reactions of Aryl Iodides with Amides, Thiols, and Phenols
Yao-Jung Chen* and Hsin-Hung Chen
*Department of Chemistry, National Chung-Hsing University, Taichung, Taiwan
402, ROC, Email: yjchen
dragon.nchu.edu.tw
Y.-J. Chen, H.-H. Chen, Org. Lett., 2006, 8, 5609-5612.
DOI: 10.1021/ol062339h
Abstract
Inexpensive 1,1,1-tris(hydroxymethyl)ethane is an efficient, and versatile tridentate O-donor ligand suitable for the copper-catalyzed cross-coupling reactions of aryl iodides with amides, thiols, and phenols to afford the corresponding desired products in good to excellent yields.
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Key Words
Ullmann Coupling, Amides, Thioethers, Diaryl Ethers
ID: J54-Y2006-3800
