Highly Active in Situ Catalysts for Anti-Markovnikov Hydration of Terminal Alkynes

Aurélie Labonne, Thomas Kribber and Lukas Hintermann*

*Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52074 Aachen, Germany, Email: lukas.hintermannoc.rwth-aachen.de

A. Labonne, T. Kribber, L. Hintermann, Org. Lett., 2006, 8, 5853-5856.

DOI: 10.1021/ol062455k

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Abstract

Complexes derived from air-stable [CpRu(6-naphthalene)]PF₆ and 6-aryl-2-diphenylphosphinopyridines efficiently catalyze the anti-Markovnikov hydration of terminal alkynes to give aldehydes.

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Key Words

Hydration of alkynes

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ID: J54-Y2006-3940