Stereospecific Palladium-Catalyzed Cross-Coupling of (E)- and (Z)-Alkenylsilanolates with Aryl Chlorides
Scott E. Denmark* and Jeffrey M. Kallemeyn
*Roger Adams Laboratory, Department of Chemistry, University of Illinois,
Urbana, Illinois 61801, Email: denmark
scs.uiuc.edu
S. E. Denmark, J. M. Kallemeyn, J. Am. Chem. Soc., 2006, 128, 15958-19959.
DOI: 10.1021/ja065988x
see article for more reactions
Abstract
A highly stereospecific cross-coupling of (E)- and (Z)-alkenyl- and styrylsilanolates with various aromatic and heteroaromatic chlorides has been achieved under catalysis by bulky, biphenyl-derived phosphines and allylpalladium chloride in THF or dioxane.
see article for more examples
Highly Stereospecific, Cross-Coupling Reactions of Alkenylsilacyclobutanes
S. E. Denmark, J. Am. Chem. Soc., 1999, 121, 5821-5822.
Key Words
Hiyama-Denmark Coupling, Arenes
ID: J48-Y2006-4030
