Efficient and Stereoselective Synthesis of Allylic Ethers and Alcohols
Jiří Pospíšil and István E. Markó*
*Département de Chimie, Université catholique de Louvain, Bâtiment Lavoisier,
Place Louis Pasteur 1, B-1348 Louvain-la-Neuve, Belgium, Email: marko
chim.ucl.ac.be
J. Pospisil, I. E. Marko, Org. Lett., 2006, 8, 5983-5986.
DOI: 10.1021/ol062433y
Abstract
A short, efficient and mild synthesis of allylic TBS ethers and allylic alcohols is based upon a unique Kocienski-Julia olefination reaction. Various allylic alcohols and allylic ethers are obtained in good to excellent yields and with high (E)-selectivity.
see article for more examples
Julia-Kocienski Reaction-Based 1,3-Diene Synthesis: Aldehyde-Dependent (E,E/E,Z)-Selectivity
F. Billard, R. Robiette, J. Pospíšil, J. Org. Chem., 2012, 77, 6358-6364.
Key Words
Modified Julia-Olefination, Allylic Alcohols
ID: J54-Y2006-4100
