Copper-Catalyzed Amidation of Allylic and Benzylic C-H Bonds
Guillaume Pelletier and David A. Powell*
*Merck Frosst Centre for Therapeutic Research, 16711 Trans Canada Highway, Kirkland, Québec H9H 3L1, Canada, Email: david_powell2merck.com
G. Pelletier, D. A. Powell, Org. Lett., 2006, 8, 6031-6034.
DOI: 10.1021/ol062514u
Abstract
A copper-catalyzed amidation of allylic and benzylic C-H is applicable to the coupling of a diverse set of hydrocarbon species with aryl, heteroaryl, and alkyl sulfonamides and is tolerant of a variety of functional groups.
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Key Words
Sulfonamides, tert-butylhydroperoxide
ID: J54-Y2006-4130