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2-Iodoxybenzoic Acid Mediated Facile Conversion of 1,3-Diols to 1,2-Diketones by Oxidative Cleavage of the C-C Bond

J. S. Yadav*, Swapan Kumar Biswas, R. Srinivas

*Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500007, India, Email:

J. S. Yadav, S. K. Biswas, R. Srinivas, Synthesis, 2006, 4237-4241.

DOI: 10.1055/s-2006-950372

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1,3-Diols undergo smooth oxidative cleavage of the C-C bond in the presence of 2-iodoxybenzoic acid (IBX) affording 1,2-diketones in excellent yields under mild conditions.

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Key Words

1,3-diols, 1,2-diketones, 2-iodoxybenzoic acid, oxidation, bond cleavage

ID: J66-Y2006-4140