Cu(I) Tol-BINAP-Catalyzed Enantioselective Michael Reactions of Grignard Reagents and Unsaturated Esters
Shun-Yi Wang, Shun-Jun Ji and Teck-Peng Loh*
*Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 639798, Email: teckpengntu.edu.sg
S.-Y. Wang, S.-J. Ji, T.-P. Loh, J. Am. Chem. Soc., 2007, 129, 276-277.
DOI: 10.1021/ja0666046
Abstract
A highly efficient regio- and enantioselective catalytic asymmetric addition of Grignard regeants to α,β-unsaturated esters is promoted by the CuI-Tol-BINAP system.
see article for more examples
Key Words
ID: J48-Y2007-0000