Silver(I) Triflate-Catalyzed Direct Synthesis of N-PMP Protected α-Aminopropargylphosphonates from Terminal Alkynes
Rajasekhar Dodda and Cong-Gui Zhao*
*Department of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249-0698, Email: cong.zhaoutsa.edu
R. Dodda, C.-G. Zhao, Org. Lett., 2007, 9, 165-167.
DOI: 10.1021/ol0627810
Abstract
A silver(I) triflate-catalyzed one-pot three-component reaction of terminal alkynes, p-anisidine, and diethyl formylphosphonate hydrate gave good yields of N-PMP protected α-aminopropargylphosphonates.
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Key Words
α-amino phosphonates, multicomponent reactions
ID: J54-Y2007-0150