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Scandium Triflate Catalyzed Transesterification of Carboxylic Esters

Nicole Remme, Katharina Koschek, Christoph Schneider*

*Institut für Organische Chemie, Universität Leipzig, Johannisallee 29, 04103 Leipzig, Germany, Email:

N. Remme, K. Koschek, C. Schneider, Synlett, 2007, 491-493.

DOI: 10.1055/s-2007-967936


Sc(OTf)3 catalyses a direct transesterification of carboxylic esters in boiling alcohols. Methyl, ethyl, isopropyl, and allyl esters were prepared from various substrates in high yields. The application of microwave irradiation led to significantly reduced reaction times.

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Key Words

carboxylic esters, catalysis, scandium, transesterification

ID: J60-Y2007-0440