Pd(0)-Catalyzed Coupling-Cyclization of 2-(2',3'-Allenyl)acetylacetates and Organic Halides: An Efficient Synthesis of 4,5-Dihydrofuran Derivatives
Shengming Ma,* Zilong Zheng, and Xuefeng Jiang
*State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, P. R. China, Email: masmmail.sioc.ac.cn
S. Ma, Z. Zheng, X. Jiang, Org. Lett., 2007, 9, 529-531.
A highly chemo-, regioselective, and efficient Pd(0)-catalyzed coupling-cyclization of 2-(2',3'-allenyl)acetylacetates with organic halides using K3PO4 as base in DMF afforded 4,5-dihydrofuran derivatives in good yields.
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