Organic Chemistry Portal

Abstracts

Search:

Pd(0)-Catalyzed Coupling-Cyclization of 2-(2',3'-Allenyl)acetylacetates and Organic Halides: An Efficient Synthesis of 4,5-Dihydrofuran Derivatives

Shengming Ma,* Zilong Zheng, and Xuefeng Jiang

*State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, P. R. China, Email: masmmail.sioc.ac.cn

S. Ma, Z. Zheng, X. Jiang, Org. Lett., 2007, 9, 529-531.

DOI: 10.1021/ol0628917 (free Supporting Information)


Abstract

A highly chemo-, regioselective, and efficient Pd(0)-catalyzed coupling-cyclization of 2-(2',3'-allenyl)acetylacetates with organic halides using K3PO4 as base in DMF afforded 4,5-dihydrofuran derivatives in good yields.

see article for more examples



Key Words

4,5-Dihydrofurans


ID: J54-Y2007-0470