Easy Access to Esters with a Benzylic Quaternary Carbon Center from Diallyl Malonates by Palladium-Catalyzed Decarboxylative Allylation
Daisuke Imao, Akihiro Itoi, Asako Yamazaki, Masamichi Shirakura, Ryota Ohtoshi, Kenta Ogata, Yohki Ohmori, Tetsuo Ohta* and Yoshihiko Ito
*Department of Molecular Science and Technology, Faculty of Engineering, Doshisha University, Kyotanabe, Kyoto 610-0394, Japan, Email: totamail.doshisha.ac.jp
D. Imao, A. Itoi, A. Yamazaki, M. Shirakura, R. Ohtoshi, K. Ogata, Y. Ohmori, T. Ohta, Y. Ito, J. Org. Chem., 2007, 72, 1534-1537.
Diallyl 2-alkyl-2-arylmalonates underwent palladium-catalyzed decarboxylative allylation quickly under mild conditions. In contrast, no reaction took place with diallyl 2,2-dialkylmalonates under the same conditions. Electron-donating phosphine ligands were found to be vital for this reaction.
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