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N,N-Dimethylglycine-Promoted Ullmann-Type Coupling Reactions of Aryl Iodides with Aliphatic Alcohols

Hui Zhang*, Dawei Ma, Weiguo Cao

*Department of Chemistry, Shanghai University, 99 Shangda Lu, Shanghai 200444, P. R. of China, Email: yehao7171shu.edu.cn

H. Zhang, D. Ma, W. Cao, Synlett, 2007, 243-246.

DOI: 10.1055/s-2007-968010


Abstract

Ullmann-type coupling reactions of aryl iodides and aliphatic alcohols occur at 110 C with N,N-dimethylglycine as the ligand, giving aryl alkyl ethers in high yields.

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N,N-Dimethyl Glycine-Promoted Ullmann Coupling Reaction of Phenols and Aryl Halides

D. Ma, Q. Cai, Org. Lett., 2003, 5, 3799-3802.


Key Words

cross-coupling, aliphatic alcohols, catalysis, ligands, aryl iodides, Ullmann Ether Synthesis, aryl ethers


ID: J60-Y2007-0730