Efficient Metal-Catalyzed Direct Benzylation and Allylic Alkylation of 2,4-Pentanediones
Magnus Rueping,* Boris J. Nachtsheim and Alexander Kuenkel
*Institute of Organic Chemistry & Chemical Biology, Johann-Wolfgang Goethe
University Frankfurt am Main, Max-von-Laue-Str. 7, D-60438 Frankfurt, Germany, Email:
m.rueping
chemie.uni-frankfurt.de
M. Rüping, B. J. Nachtsheim, A. Künkel, Org. Lett., 2007, 9, 825-828.
DOI: 10.1021/ol063048b
see article for more reactions
Abstract
A highly effective bismuth-catalyzed benzylation and allylic alkylation of 2,4-pentanediones with free alcohols provides the corresponding monoalkylated dicarbonyl compounds in high yields after short reaction times. In addition, a new route to substituted indenes is presented.
see article for more examples
An Efficient Metal-Catalyzed Hydroalkylation
M. Rüping, B. J. Nachtsheim, A. Künkel, Synlett, 2007, 1391-1394.
Key Words
ID: J54-Y2007-0740
