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A Rapid and Efficient Synthesis of Benzimidazoles Using Hypervalent Iodine as Oxidant

Li-Hua Du, Yan-Guang Wang*

*Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. of China, Email:

L.-H. Du, Y.-G. Wang, Synthesis, 2007, 675-678.

DOI: 10.1055/s-2007-965922


Various 2-arylbenzimidazoles were synthesized from phenylenediamines and aldehydes via a one-step process using hypervalent iodine as oxidant. This method features mild conditions, short reaction times, high yields, and a simple procedure.

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Key Words

benzimidazoles, iodobenzene diacetate (IBD), oxidations, o-phenylenediamines

ID: J66-Y2007-0750