Metal Triflate Catalyzed Reactions of Alkenes, NBS, Nitriles, and TMSN3: Synthesis of 1,5-Disubstituted Tetrazoles
Saumen Hajra,* Debarshi Sinha and Manishabrata Bhowmick
*Department of Chemistry, Indian Institute of Technology, Kharagpur 721 302, India, Email: shajrachem.iitkgp.ernet.in
S. Hajra, D. Sinha, M. Bhowmick, J. Org. Chem., 2007, 72, 1852-1855.
DOI: 10.1021/jo062432j (free Supporting Information)
A versatile and highly efficient Zn(OTf)2-catalyzed one-pot reaction of alkenes, NBS, nitriles, and TMSN3 gives various 1,5-disubstituted tetrazoles containing an additional α-bromo functionality of the N1-alkyl substituent.
see article for more examples