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General, Mild and Efficient Synthesis of β-Enaminones Catalyzed by Ceric Ammonium Nitrate

Vellaisamy Sridharan, Carmen Avendaño, J. Carlos Menéndez*

*Departamento de Química Orgánica y Farmacéutica, Facultad de Farmacia, Universidad Complutense, 28040 Madrid, Spain, Email:

V. Sridharan, C. Avendaño, J. Carlos Menéndez, Synlett, 2007, 2133-2142.

DOI: 10.1055/s-2007-973862


Ceric ammonium nitrate catalyzes the reaction between aromatic or aliphatic primary amines and a variety of β-dicarbonyl compounds, including β-ketoesters, β-ketothioesters and β-diketones to give β-enaminones in good to excellent yields at room temperature in short reaction times.

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Key Words

enaminones, ceric ammonium nitrate, lanthanides,Lewis acids, β-dicarbonyl compounds

ID: J60-Y2007-0920