General, Mild and Efficient Synthesis of β-Enaminones Catalyzed by Ceric Ammonium Nitrate
Vellaisamy Sridharan, Carmen Avendaño, J. Carlos Menéndez*
*Departamento de Química Orgánica y Farmacéutica, Facultad de Farmacia,
Universidad Complutense, 28040 Madrid, Spain, Email: josecm
farm.ucm.es
V. Sridharan, C. Avendaño, J. Carlos Menéndez, Synlett, 2007, 2133-2142.
DOI: 10.1055/s-2007-973862
Abstract
Ceric ammonium nitrate catalyzes the reaction between aromatic or aliphatic primary amines and a variety of β-dicarbonyl compounds, including β-ketoesters, β-ketothioesters and β-diketones to give β-enaminones in good to excellent yields at room temperature in short reaction times.
see article for more examples
Key Words
enaminones, ceric ammonium nitrate, lanthanides,Lewis acids, β-dicarbonyl compounds
ID: J60-Y2007-0920
